Game of Thrones latest death is a tough one to take and

first_img Game of Thrones season 8, episode 4: How to watch, leaks, recaps, avoiding spoilers and how to stream HBO without cable Thanos vs. Game of Thrones Night King: Here’s who’d win Game of Thrones season 8: How to adjust your TV for a cinematic picture Here’s me thinking this episode would be a celebration #GameOfThrones pic.twitter.com/1BQiCa6aQw— Joeyyy (@_Joseph590) May 6, 2019 The 38 most gut-wrenching Game of Thrones deaths, ranked Comments OH NOOOOOO. NOT THE DRAGONNNNNNN. #GoT #ThronesYall pic.twitter.com/52CoNbI6oc— Brittany Packnett (@MsPackyetti) May 6, 2019 Game of Thrones images too dark? We can help *MILD SPOILERS*… Culture TV and Movies Now playing: Watch this: WHAT THE WHOLE FUCK IS HAPPENING?!?!?! THIS FUCKIN ASSHOLE!!!!!!!!!! BURN THEM ALL!!! @HBO @GameOfThrones #GoT #Season8 #DemThrones #Episode4— T-Pain (@TPAIN) May 6, 2019 Did we just lose another dragon?!? Wtf?!? #GameofThrones pic.twitter.com/HTngwEfAJ6— the.blogging.jedi (@TonyStarksWard) May 6, 2019 Rhaegal after being shot by Euron three times #GOT #GameofThrones pic.twitter.com/PcghYP18oV— colby (@originalgenome) May 6, 2019 Related stories Not the dragon!! Not him!! He should stay back! #GameofThrones pic.twitter.com/fguDMwcx6K— Yerlin (@Marlet_Yerlin) May 6, 2019 NOOOOOO THAT DID NOT JUST HAPPEN #GameOfThrones pic.twitter.com/Li74D2gUiL— t h o m a s (@RIPeterParker_) May 6, 2019 Tags Me: “Oh, he only got hit by one spear he might be okay…”*Gets shot in the throat***Sinks to the bottom of the ocean**#GameofThrones #Rhaegal pic.twitter.com/uN1tbkEqyk— Dr.Pibb🌶️ (@MichaelDiAcri) May 6, 2019 Why? HBO Look, we’re used to heart-wrenching deaths on Game of Thrones, but this is different. This totally sucks.What are you doing to us here? Why would you do this?OK, here’s your obligatory spoiler warning for episode 4 of this final season. game-of-thrones-spoilersCan we talk now? OK, let’s talk.They killed a dragon. They killed another goddamn dragon. Rhaegal to be specific. People are upset. Hell, I’m upset. The Night King doing the whole “you’re an ice dragon now” to Viserion was pretty bad, but this might actually be worse.Mainly because of who did the killing.  38 Photos I can’t handle Dany losing anymore dragons #GOT #GameofThrones pic.twitter.com/zce6jJxIFK— colby (@originalgenome) May 6, 2019 5:13 Rhaegal didn’t deserve surviving his ice dragon brother to be killed by bitch ass Euron!!!! #GoT pic.twitter.com/F2XjqDPLeB— MissFit Harley (@MissfitHarley) May 6, 2019 And then there was 1! 😢😩 #GameOfThrones #GOT— MeLAnIn JunKIE (@xLuv_N_Myself) May 6, 2019 Share your voice 8 RIP Rhaegal, you were almost all healed up for battle, you sweet baby you. RIP Missandei, you were the realest and you had the most poppinest wash-n-go in all the 7 Kingdoms until the very end. pic.twitter.com/MYA6KisIWh— 🐝HTHMSCTHMING🐝 (@_BeNiceOrLeave) May 6, 2019 RIP Rhaegal, you were almost all healed up for battle, you sweet baby you. RIP Missandei, you were the realest and you had the most poppinest wash-n-go in all the 7 Kingdoms until the very end. pic.twitter.com/MYA6KisIWh— 🐝HTHMSCTHMING🐝 (@_BeNiceOrLeave) May 6, 2019 Rhaegal died thanks to Euron Greyjoy and Cersei’s gigantic dragon crossbow thing — this is a problem. Euron sucks. Not in a good, “Hi, I’m Joffrey the best villain in TV history kind of way.” In a bad, “my character is a bit weird and people don’t really like me” kind of way. In wrestling, they call this “X-Pac heat.”Anyway, Twitter got real upset about Rhaegon essentially getting murked by Euron’s fleet. Rightfully so in my humble opinion. With Rhaegal kicking the bucket and Jon Snow putting Ghost up for adoption, it was truly a difficult episode for the pets. Game of Throneslast_img read more

Plastic products could easily become electronic with first moldable allcarbon circuits

Plastic products could easily become electronic with first moldable allcarbon circuits

first_img More information: Dong-Ming Sun, et al. “Mouldable all-carbon integrated circuits.” Nature Communications. (2013) DOI: 10.1038/ncomms3302Dong-Ming Sun, et al. “Flexible high-performance carbon nanotube integrated circuits.” Nature Nanotechnology. (2011) DOI: 10.1038/nnano.2011.1 © 2013 Phys.org. All rights reserved. (Left) All-carbon device fabricated on a flexible polymer substrate. (Right) The ON and OFF currents of the all-carbon transistor for different bending levels. Credit: Sun, et al. ©2013 Macmillan Publishers Limited The new circuits are composed of different types of carbon materials, with the active channels and passive elements consisting of carbon nanotubes, and the dielectric layers and substrates consisting of the plastic polymers polymethyl methacrylate (PMMA) and polyethylene naphthalate (PEN), respectively. Journal information: Nature Communications In a new study, researchers have for the first time developed integrated circuits that are composed entirely of flexible carbon-based materials, and can be molded into various shapes using the same molding techniques used for shaping plastic products. The development could allow electronic circuits to be easily integrated into a variety of plastic products, including everything from medical devices to plastic products around the home.”The plastic cases of smart phones and tablets, which are just protecting the electronic devices inside, will have electronic functions such as displays, touch sensors, and so on, making smart phones more functional and fashionable,” Yutaka Ohno of Nagoya University in Japan and Aalto University in Finland told Phys.org. “By integrating other functions such as displays and sensors into plastic devices, we are thinking of developing 3D interactive information communication devices, which can be used in medical settings, for example.”Ohno, along with Dong-Ming Sun of Nagoya University and their coauthors, have published a paper on the moldable all-carbon integrated circuits in a recent issue of Nature Communications.”The key point in our design is that the all-carbon devices are made of carbon nanotubes and polymers, and they exhibit better flexibility and stretchability compared with devices fabricated from rigid metals and oxide insulators, making the devices much more flexible and elastic,” Sun said. “The results of this study make it possible to achieve a fusion of electronic devices with plastic products, which can lead to the creation of plastic electronic devices that feature both designability and functionality.” Carbon nanotube transistors could lead to inexpensive, flexible electronics (Phys.org) —There has been a great deal of research lately on flexible electronics, but so far these devices (which are mostly made of carbon) still use metal electrodes and oxide insulators, and these rigid materials limit device flexibility. Some polymers and ionic liquids have been introduced as flexible alternatives, but have poor performance in terms of high operating voltages and low operating speeds, respectively.center_img Citation: Plastic products could easily become electronic with first moldable all-carbon circuits (2013, August 23) retrieved 18 August 2019 from https://phys.org/news/2013-08-plastic-products-easily-electronic-moldable.html (Left) A dome-shaped all-carbon device (scale bar, 10 mm). Inset: magnified photograph (scale bar, 1 mm). (Right) Illustration of the cross-section of the air-assisted thermopressure-forming apparatus used to mold the all-carbon device. Credit: Sun, et al. ©2013 Macmillan Publishers Limited Unlike the polymers and ionic liquids that have been previously tried as materials for flexible dielectrics, the PMMA that the researchers used here can enable transistors and integrated circuits to operate at low voltages and high speeds. The low operating voltage can be explained in part by the sparse, network-like carbon nanotube thin film used as the channels, which enhances coupling between the channel and gate electrode compared with using thick polymers as the channels.Previously, the researchers successfully fabricated a thin-film transistor with a mobility greater than 600 cm2V-1s-1 by developing a technology for forming a long, yet pure, carbon nanotube film on plastic. In the new study, the researchers made further progress on the optimization of the film-forming technology, achieving a mobility of 1,027 cm2V-1s-1. This mobility is higher than that of a MOSFET, which uses monocrystalline silicon, and the researchers describe it as an astonishing value for a thin-film transistor fabricated on a plastic substrate.Because these all-carbon devices are made of carbon nanotubes and polymers, they exhibit better flexibility and stretchability compared with devices fabricated from rigid metals and oxide insulators. Perhaps the most useful feature of the all-carbon circuits is their moldability, which the researchers demonstrated by heating and blowing a planar substrate to form a dome-shaped structure. The 3D dome is stretched during this molding process without cracking, in sharp contrast to rigid materials such as metals. The extreme stretchability of both the passive and active elements of the devices can allow them to be formed using the same molding techniques used today to shape plastic products. In order to scale up the devices, the researchers note that it will be important to grow carbon nanotubes with a uniform length and diameter to minimize current variation. Eliminating metallic nanotubes can also offer further performance improvements. They also hope to use fabrication methods other than the lithographic methods they used here.”It is desirable to form carbon nanotube channels and wirings at atmospheric pressure and low temperature by high-throughput printing techniques rather than current lithographic techniques,” Sun said. Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. , Nature Nanotechnologylast_img read more

Elderly woman stabbed in Salt Lake area

Elderly woman stabbed in Salt Lake area

first_imgKolkata: An elderly woman was stabbed by an unknown miscreant who had come to her apartment in Salt Lake area seeking monetary help for his ailing mother on Friday.According to locals, one Jayashree Chakraborty aged about 71 years, was alone in a flat inside Cluster III of Purbachal Housing Complex. Around 11:30 am, Jayashree heard someone knock on the door and she thought that it might be her grandson who has come back from school. Without asking, she opened the door and saw the man at the door, wearing a helmet. Also Read – Rain batters Kolkata, cripples normal lifeSources informed that the miscreant asked Jayashree for money and before she could react, he started stabbing her. When she screamed, he took some cash from her bag and fled. Jayashree then somehow managed to alert her neighbours. Seeing her bleed, her neighbours immediately called Jayashree’s son Anish and narrated the incident. Jayashree was admitted to a private hospital in Salt Lake with serious stab injuries. Later, Bidhannagar South police station was informed. Sleuths went to the apartment and investigated the incident spot. Also Read – Speeding Jaguar crashes into Mercedes car in Kolkata, 2 pedestrians killedThere was no CCTV installed in the housing. Due to this, the cops are in the dark about the miscreant. Later police met Jayashree and recorded her statement. Following this, police were able get hold of a CCTV camera footage on the road where a person was seen. As per Jayashree’s description, police identified several similarities with the person seen in the footage. It is suspected that the miscreant did not have any intention of robbery. Thus, he did not take any ornaments which could be robbed easily as Jayashree was not in a condition to resist. To know if the Chakraborty family had any enmity with anyone, sleuths are questioning them. The security guards of the housing complex have also been questioned.last_img read more

SES has successfully launched its Astra 2F satelli

SES has successfully launched its Astra 2F satelli

first_imgSES has successfully launched its Astra 2F satellite, which will serve the 28.2°/28.5° East position for the UK and Ireland.The Astrium-build satellite is the first of three that will provide replacement and growth capacity for the UK and Ireland. From October next year they will also use spectrum granted by Media Broadcast following a 2005 agreement.The Astra 2F satellite also provides Ku-band capacity for pan-European services and for sub-Saharan Africa. A Ka-band payload will also allow SES Broadband Services to support download speeds of up to 20Mps.last_img

Our greenways and parks play a key role in encour

Our greenways and parks play a key role in encour

first_img“Our greenways and parks play a key role in encouraging the public to get out into the outdoors and choose active travel options which can have a knock on positive effect on the environment and on people’s health and wellbeing.”Paul McNaught from the Department for Communities said: “This investment will have a transformative effect on Kilfennan Valley Park and enhance the City’s every growing greenway network.“As we have seen from previous upgrade projects of this nature, the completed works will make the park a more attractive and enjoyable amenity for users, encouraging active lifestyle choices and bringing communities together in a communal space.” Linda Watson, co-ordinator of the Caw/Nelson Drive Action Group added: “Local residents are delighted and excited that these upgrade works have begun. “The finished project will create a safer, more comfortable and accessible space for residents to use for leisure and active travel.“The community group have worked closely with other stakeholders to bring the project to this key stage.“We would like to express our gratitude to both Derry City and Strabane District Council and the Department for Communities for making the funding available for the plans to become a reality.”Major upgrade works start on Kilfennan Valley Park Greenway was last modified: March 21st, 2019 by John2John2 Tags: WORK has started on significant upgrade works on the Kilfennan Valley Park Greenway.The environmental improvement scheme will include a number of enhancements to the existing path network in the park including improved drainage, the installation of lighting and a new crossing point at the Rossdowney Road to Kilfennan Valley Park.The £549,000 investment is being jointly funded by Derry City and Strabane District Council and the Department for Communities and will complement the new Clooney Greenway project to create a sustainable travel corridor in the heart of the Waterside. It will include new pathway links and crossing points at Woodburn Urban Park, Rossdowney Road, Rossdale Road and Rossmore Road.Mayor of Derry City and Strabane District Council, Councillor John Boyle, welcomed the start of work on the project.“The Waterside Greenway infrastructure has improved significantly in recent years and this project will further add to the existing network and enhance the experience of users of the Kilfennan Valley Park Greenway.“There are also exciting plans to further develop the North West Greenway network including three cross border routes from Derry to Buncrana via Bridgend, Muff to Derry via Culmore and Lifford to Strabane. ShareTweet CAW/NELSON DRIVE ACTION GROUPDEPARTMENT FOR COMMUNITIESDerry and Strabane CouncilLINDA WATSONMajor upgrade works start on Kilfennan Valley Park GreenwayMayor John BoyleROSSDOWNEY ROADlast_img read more

Jim Rickards Secret Accounting Career In

first_img Jim Rickards’ Secret Accounting Career In 1977, before most of today’s Wall Street analysts were even born, Jim Rickards was doing complex tax and accounting work at Citibank. Now he has uncovered the biggest accounting hoax since Enron… one that could wipe out millions of Americans. Will you be a victim of this accounting scandal? Click here to find out. Recommended Links One of the world’s most important markets continues to flash danger signs… Regular readers know we keep close tabs on the bond market. The bond market is where individuals, companies, and governments go to borrow money. The U.S. bond market is about twice as large as the U.S. stock market. That’s one reason the bond market can signal trouble before the stock market. •  The junk bond market is where companies with shaky finances borrow money… Junk bonds are riskier than bonds issued by healthy companies, so they pay higher yields. When the economy slows, companies in bad financial shape often feel it first. That’s why economic trouble tends to show up in the junk bond market early on. •  Junks bonds are set to have their first down year since the financial crisis… On Monday, The Wall Street Journal reported that U.S. junk bonds are down 2% on the year. If they end the year down, it would be their first losing year since 2008. •  Bond defaults are at their highest level since 2009… Worldwide, companies have already defaulted on $95 billion in debt this year. That translates to 102 corporate defaults, or 42 more than last year. U.S. companies account for over half of these defaults. •  Moreover, the U.S. energy sector accounts for 26% of global defaults this year… Casey readers know the U.S. energy market is struggling… Yesterday, the price of oil hit a new six-year low. It’s plunged 66% since last June. And the price of natural gas has plunged 56% since last summer. Most oil and gas companies’ profits have plummeted. As a result, companies that borrowed big before energy prices crashed are struggling to pay back their loans. •  Credit rating agency Standard & Poor’s says half of all energy junk bonds are distressed… A distressed bond has a high risk of default. And the trouble isn’t isolated to energy bonds. Last week, Bloomberg Business reported that 20% of all U.S. junk bonds are now distressed. That’s the highest level since September 2009. •  Corporate defaults could double in 2016… So far, only 2.6% of junk bonds have defaulted this year. However, that figure will likely jump soon. On Monday, The Wall Street Journal reported that defaults are expected to nearly double to 4.6% next year. If that happens, junk bonds would pass their 30-year average default rate of 3.8%. That also hasn’t happened since 2009. •  Meanwhile, the U.S. stock market is showing big cracks… Last week, we explained how a handful of huge companies are making the U.S. stock market look healthier than it really is. This includes Google (GOOG), Microsoft (MSFT), Amazon (AMZN), Facebook (FB), and Netflix (NFLX). When most investors talk about “the stock market,” they’re talking about the popular S&P 500 index. The S&P 500 is weighted by company size, which means bigger companies affect its performance far more than smaller companies. For example, Google is the second-largest company in the S&P 500. It’s up 43% on the year. Amazon is the sixth-largest company. It’s up 113%. Facebook is the eighth-largest. It’s up 35%. Meanwhile, S&P 500 stocks are trading 18% below their 52-week highs, on average. •  This chart shows what’s really happening in the stock market… It’s one of the most important charts in the world right now… It compares the S&P 500 with a version of the S&P that gives equal weight to every company. In the equally weighted S&P, toymaker Hasbro (HAS) has as much weight as Google, which is 61 times bigger than Hasbro. Only way for Americans to legally pay close to ZERO taxes 70-year-old multimillionaire has revealed greatest – and least known – American tax “loophole.” Click here to get the full details. – •  The U.S. stock market flashed the same red flag in 1999… A handful of big stocks pulled the major indices higher that year, while most U.S. stocks struggled. By 2000, the S&P 500 turned down and went on to lose 48% in 32 months. The NASDAQ crashed 78% in the same time. The U.S. stock market is like a healthy-looking tree that’s actually rotting on the inside. Eventually, when the largest stocks can’t prop it up anymore, the entire tree is going to fall. •  We recommend investing with extreme caution right now… You should hold a significant amount of cash and some physical gold. You may also want to hedge your portfolio by shorting (betting against) stocks likely to crash hard during the next big downturn. This could mean shorting very expensive stocks. It could also mean shorting businesses that will struggle to make money during a prolonged economic slowdown. We recently recorded a video presentation on the topic of investing during difficult times. Doug Casey, founder of Casey Research, gave his advice on how to protect your money and make more money during a major market collapse. Click here to watch – it’s free. Chart of the Day Here’s another clue U.S. stocks are topping out… Professional investors often look at “spreads” to gauge the market’s strength. A spread is the difference between two prices or interest rates. One important spread subtracts the interest rate paid by junk bonds from the interest rate paid by U.S. Treasuries. U.S. Treasuries are bonds issued by the U.S. government, which is widely considered one of the safest borrowers in the world. Junk bonds, on the other hand, are issued by riskier borrowers. Today, the interest rate on Treasuries is 2.1% and the average interest rate on junk bonds is 8.8%. So the “spread” is 6.7%. When the economy is humming along, this spread typically gets smaller. Companies generally make good on their bonds during good economic times, so investors don’t demand a big interest rate premium. However, when the spread starts to get bigger, it’s a sign of trouble ahead for the stock market. For example, this spread started to get bigger in the summer of 2007. Smart investors knew this was a bad sign. They got out of the stock market and saved a ton of money. As you likely remember, the S&P 500 peaked in October 2007, and went on to crash 57%. For the first time in four years, this spread is getting significantly bigger. As you can see, the U.S. stock market and spread moved together while stocks were in a clear-cut bull market through mid-2014 (the spread is inverted on the chart below). Then, they diverged. The spread has more than doubled, while the S&P 500 remains near all-time highs. This is another reason to be very cautious in the stock market today. These two indices tracked each other for most of 2015. However, in recent weeks the S&P 500 has pulled ahead of the equally weighted S&P, which is now down 4% on the year. This is a big red flag. It’s confirmation that a few big companies are holding up the stock market. — Regards, Justin Spittler Delray Beach, Florida December 11, 2015 We want to hear from you. If you have a question or comment, please send it to feedback@caseyresearch.com. We read every email that comes in, and we’ll publish comments, questions, and answers that we think other readers will find useful.last_img read more

CDC selects UMass Amherst biostatistician model that helps predict influenza outbreaks

first_imgReviewed by James Ives, M.Psych. (Editor)Dec 13 2018When the Centers for Disease Control and Prevention was looking for a preferred flu prediction model for use in its flu-forecasting challenge this season, an influenza-tracking model developed by a team led by biostatistician Nicholas Reich at the University of Massachusetts Amherst rose to the top and will be one of its principal prediction tools, Reich says.Reich, whose UMass-led collaborative is made up of six teams, says, “We competed in the CDC challenge last year and out of 30 models the CDC received to help predict the flu season, ours was the second best. This year we’re re-tooling some of our models and the CDC has chosen our model to try to optimally predict seasonal influenza outbreaks.””It’s a nice accomplishment,” he adds. “Apparently our collaborative approach that fuses multiple different models together impressed them as being better and more reliable than all of the other approaches they have seen over the past few years. We hope we can contribute quite a bit to this year’s efforts.”In an international group dubbed the “FluSight Network,” Reich at UMass Amherst’s School of Public Health and Health Sciences, with colleagues at Carnegie Mellon University, the CDC, Columbia University, Los Alamos National Laboratory, Mount Holyoke College, and a consulting group from South Africa called Protea Analytics, issue a new flu season forecast starting in late fall every Monday for public health researchers and practitioners. It compares the flu trajectory this year to past years.”This entire effort is public, so anyone can go to the website and see the forecasts and even get at the raw data underlying them,” Reich points out. They work year-round to develop a way for all their models to work together to make a single best forecast for influenza, a method they call a “multi-model ensemble approach.”In addition to his work on the influenza-tracking team, Reich writes an occasional blog on “what we are, and are not, ready for” when it comes to flu season. Last September, he was one of just four influenza forecasters in the nation invited to participate in the CDC’s first flu pandemic simulation workshop, which included mock press conferences by officials including the CDC director. The exercise allowed the agency to run through several scenarios about how a flu pandemic might be forecast from early data, how it could be tracked and how integrating advanced analytic processes into decision-making might assist with those projections.Among other things, Reich says, the workshop was a recognition by the CDC that a network of forecasters that exists in academia and industry today but not in the public sector, might help decision-makers to use the data as one of their inputs when making choices.Related StoriesNaturally occurring human antibody reveals hidden weakness in influenza virusStudy provides insight on how two proteins help influenza A virus to fight its way to cellsStudy uncovers potential new strategy to treat influenza AHe says, “We work very closely with our collaborators at the CDC. Without their vision and careful design of this challenge five years ago, we wouldn’t be where we are today. This collaboration has added a lot of value to the laudable efforts that they have made over these years to integrate data and modeling into real-time public health decision-making,” he adds. “The value of the ensemble approach is becoming clear to all observers and that workshop helped to demonstrate it.”Now in its second year of participating in the CDC challenge, the FluSight Network gets a little better each year at refining flu projection models, Reich says. These help the experts prepare public flu messages, assess disease severity and regional incidence, project peak impact and other factors important to public health officials.Not only health professionals, but health writers and reporters watch the CDC’s weekly updates each week, the biostatistician says. “The first question of the season is when is it going to start. That is, when will the number of cases go above the baseline of flu activity by region, which is the first checkpoint of every season. Hospitals, clinics, family physicians all keep their eye on this information to help them prepare.””So far this flu season, a few regions of the U.S., including the Northeast, have been seeing slightly higher levels of flu-like activity than normal, but the most recent data suggest that the levels are still below what the CDC defines as a ‘baseline’ level of activity,” he points out.”That said, our models are saying that we should perhaps expect a bit of an early onset to the season in the Northeast and a few other regions,” Reich adds. “The ensemble model isn’t picking up a clear signal yet about how different from a normal year the peak incidence might be in terms of timing or severity. In coming weeks, we think the models may show a bit more separation from the historical average. Right now, though, it’s a little like looking at a 30-day weather forecast and trying to use that to decide whether it’s going to snow on any particular day. Our models just can’t reliably see that far into the future at the moment.”For their prediction efforts, each team submits eight seasons of influenza forecasts from the past to the UMass-led model. “This approach allows us to do better than a simple average of all models,” Reich says, “because we can employ them proportionally based on their success. Each model has different strengths based on the data or the methodological approach they use. Some models this season are incorporating data from a variety of internet data, including signals from Twitter, Google Search activity and Wikipedia.” Source:https://www.umass.edu/newsoffice/article/umass-amherst-biostatistician-and-nationallast_img read more

Huge Malaria vaccine trial in Malawi

first_imgPeter Sands, Executive Director of the Global Fund in his statement added, “To step up the fight against malaria, we need every available tool. If this pilot shows that RTS,S is a cost-effective tool against malaria, it will help us save more children’s lives.” Dr Seth Berkley, CEO of Gavi in his statement said, “Malaria is still one of the biggest killers of children worldwide, taking the lives of over 200,000 children every year. These pilots will be crucial to determine the part this vaccine could play in reducing the burden this disease continues to place on the world’s poorest countries.” The vaccine known as RTS,S or Mosquirix, would be administered to children up to 2 years of age. After Malawi, the vaccine would be introduced in its pilot trial phase in Ghana and Kenya in the coming weeks. In these African countries malaria remains a menace and kills with an alarming frequency of one child every two minutes. In Africa, over 250,000 children die due to malaria annually. The risks of dying due to malaria and its complications are highest among children under the age of five years. Across the world, malaria kills 435,000 people annually of which most are children says WHO. The team leading the pilot trial would roll out the programme and help to generate information and experience with the RTS,S malaria vaccine so that WHO can devise its policy recommendations regarding the vaccine. The utility and efficacy of the vaccine in reducing childhood deaths, safety of the vaccines, if the parents were willing to bring their children for the routine four doses of the vaccine and its general acceptance would all be studied.WHO officials add, that this new malaria vaccine would be part of the malaria control programme. WHO recommends other major measures for malaria control including insecticide-treated bed nets, use of insecticides indoors and routine testing for malaria in case of fever and its early treatment.This pilot programme is a collaboration between the WHO and ministries of health in Ghana, Kenya and Malawi along with PATH, a non-profit organization and makers of the vaccine GSK. GSK is donating up to 10 million vaccine doses for this pilot project. This pilot project is receiving financial support from Gavi, the Vaccine Alliance; the Global Fund to Fight AIDS, Tuberculosis and Malaria; and Unitaid. Contributions in kind are being provided by WHO, PATH and GSK. Steve Davis, President and CEO of PATH said in a statement, “We salute WHO and Malawi for their leadership in realizing this historic milestone and we look forward to the start of vaccination in Ghana, and then Kenya later this year. A vaccine for malaria is among many innovations needed to bring an end to this disease, and we proudly stand with all countries and our many partners in progressing towards a malaria-free world.” Dr Matshidiso Moeti, WHO Regional Director for Africa, in a statement said, “Malaria is a constant threat in the African communities where this vaccine will be given. The poorest children suffer the most and are at highest risk of death. We know the power of vaccines to prevent killer diseases and reach children, including those who may not have immediate access to the doctors, nurses and health facilities they need to save them when severe illness comes. This is a day to celebrate as we begin to learn more about what this tool can do to change the trajectory of malaria through childhood vaccination.” Malaria vaccine trial in Malawi. Image Credit: WHO This malaria vaccine took three decades to make say researchers. Until now it remains the only vaccine against malaria. Phase 3 clinical trials with the vaccine have been conducted in Africa between 2009 and 2014. These clinical trials with this vaccine show that this vaccine could prevent 40 percent of malaria cases and 30 percent of fatal severe malaria cases. Dr David Schellenberg, one of the researchers who helped develop the vaccine said in a statement, “There were seven countries participating in a large trial where over 15,000 children participated. [The trial] showed pretty clearly that this vaccine is safe and it is efficacious in terms of its ability to prevent clinical malaria episodes and also severe malaria episodes.”#Malawi 🇲🇼: A baby girl named Gloria was first in line for a #malariavaccine at the Muotcha HIV Testing & Counseling Centre in the town of Balaka. pic.twitter.com/EYGh46XcB7— WHO African Region (@WHOAFRO) April 24, 2019 Similarly Lelio Marmora, Executive Director of Unitaid added, “The malaria vaccine is an exciting innovation that complements the global health community’s efforts to end the malaria epidemic. It is also a shining example of the kind of inter-agency coordination that we need. We look forward to learning how the vaccine can be integrated for greatest impact into our work.” According to WHO Director-General Dr Tedros Adhanom Ghebreyesus in a statement, “We have seen tremendous gains from bed nets and other measures to control malaria in the last 15 years, but progress has stalled and even reversed in some areas. We need new solutions to get the malaria response back on track, and this vaccine gives us a promising tool to get there. The malaria vaccine has the potential to save tens of thousands of children’s lives.” Further Reading What is Malaria? Malaria Causes Malaria Mechanism Malaria Diagnosis Malaria Prevention Malaria Treatment Malaria Epidemiology Malaria Society And Culture Malaria Symptoms The pilot programme is slated to reach around 360,000 children annually in the three target nations. The areas covered would be regions where malaria transmission is high and the vaccine would be of greater help say officials. There would be four doses of the vaccine for each child – 3 doses to be administered between 5 and 9 months of age and the fourth dose to be administered at around the age of 2 years.A PATH white paper on this project says, “Looking ahead The pilot implementation was designed as a six-year program, including preparation, and the evaluations are now expected to be completed by 2023. Its goal is to enable an updated WHO policy recommendation on the possible broader use of RTS,S in African children by generating additional evidence on feasibility, impact, and safety—all in the context of routine use.” By Dr. Ananya Mandal, MDApr 24 2019This week the African nation of Malawi became one of the first of the planned three to launch a pilot trial for a novel vaccine against malaria. The news and the efforts were lauded by the World Health Organization (WHO). Dr Thomas Breuer, Chief Medical Officer of GSK Vaccines in a statement said, “Delivering the world’s first malaria vaccine will help reduce the burden of one of the most pressing health challenges globally. This novel tool is the result of GSK employees collaborating with their partners, applying the latest in vaccine science to contribute to the fight against malaria. We look forward to seeing the results of the pilot, and in parallel, are working with WHO and PATH to secure the vaccine’s sustained global health impact in the future.”last_img read more

Were the Vikings Smoking Pot While Exploring Newfoundland

first_img 30 of the World’s Most Valuable Treasures That Are Still Missing The discovery of cannabis pollen near a Viking settlement in Newfoundland raises the question of whether the Vikings were smoking or eating pot while exploring North America. The researchers also found evidence the Vikings occupied this outpost for more than a century, way longer than previously believed. Located in northern Newfoundland, the site of L’Anse aux Meadows was founded by Vikings around A.D. 1000. Until now, archaeologists believed that the site was occupied for only a brief period. The new research, published today (July 15) in the journal Proceedings of the National Academy of Sciences, suggests that the Vikings lived there possibly into the 12th or even the 13th century. [In Photos: Viking Outposts Possibly Found in Canada]Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65940-were-vikings-smoking-pot-in-newfoundland.html?jwsource=cl已复制直播00:0000:3500:35  Bog finds In August 2018, an archaeological team excavated a peat bog located nearly 100 feet (30 meters) east of the Viking settlement at L’Anse aux Meadows. They found a layer of “ecofacts” — environmental remains that may have been brought to the site by humans — that were radiocarbon dated to the 12th or 13th century. These ecofacts include remains of two beetles not native to Newfoundland — Simplocaria metallica, from Greenland, and Acidota quadrata, from the Arctic. The layer also held pollen from Juglans (walnuts) and from Humulus (cannabis), two species that don’t naturally grow at L’Anse aux Meadows; rather, the Vikings could have picked up all of these plant and animal species when they sailed south. [Photos: 10th-Century Viking Tomb Unearthed in Denmark] They also found the remains of dung from grazing caribou, as well as remains of wood and charcoal. The layer from the peat bog is similar to other “cultural layers from across the Norse North Atlantic,” the archaeological team wrote in the journal article. More evidence Additionally, the archaeologists performed Bayesian analysis — a type of statistical analysis — on radiocarbon dates from artifacts previously excavated at L’Anse aux Meadows. That analysis also suggested Viking occupation for up to 200 years. “This does not imply a continuous occupation,” the researchers wrote, noting that the Vikings could have abandoned and reoccupied L’Anse aux Meadows when it suited them. Did the Vikings use pot in Newfoundland? The finding of cannabis pollen raises the question of whether the Vikings used cannabis for making clothes or for medicinal-recreational purposes while they explored North America. Paul Ledger, the lead author of the paper and a postdoctoral fellow at Memorial University of Newfoundland urged caution on the interpretation of the findings, noting that pollen can easily be carried by the wind. Ledger urged caution on the interpretation of the findings, noting that pollen can easily be carried by the wind. It’s also possible that some of the other “ecofacts” were brought to the peat bog by indigenous peoples who lived in Newfoundland, and not by the Vikings. [Fierce Fighters: 7 Secrets of Viking Seamen] Ultimately, “the results presented here [in the journal article] pose more questions than answers,” the archaeological team wrote. Reaction from other Viking researchers Viking researchers not affiliated with the research team urged caution about the results. “I think it is too early to draw any conclusions,” said Birgitta Wallace, a senior archaeologist emerita with Parks Canada who has done extensive research on the Vikings in North America. Wallace told Live Science that she isn’t convinced that the Vikings left behind these ecofacts. “I think it is highly unlikely that the Norse [another word for Vikings] would have returned in the 12th and 13th centuries, as there are no structures on the site from that period that could be Norse,” Wallace said. “We do know that there were indigenous people, ancestors of the Beothuk, on the site at that time.” Patricia Sutherland, a visiting scientist at the Canadian Museum of Nature who has also done extensive research on the Vikings in North America, said that while the Vikings could have been in Newfoundland during the 12th or 13th centuries, it is too early to say for sure. “It seems premature to suggest such a scenario on the basis of the ‘ecofacts’ listed in the paper,” Sutherland said. It’s possible that some of the beetles and plant pollen found in the layer were brought to L’Anse aux Meadows by the Vikings around A.D. 1000, and they continued to flourish after the Vikings left, Sutherland said. The research team plans to continue their work at L’Anse aux Meadows in August, Ledger said. Photos: Viking Warrior Is Actually a Woman The 25 Most Mysterious Archaeological Finds on Earth Editor’s note: This article was updated to fix a statement about the interpretation of the cannabis pollen. Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoGundry MDThis Is What Happens To Dark Spots (When You Do This Every MorningGundry MDUndoEditorChoice.comFunny Signs You Can’t Un-SeeEditorChoice.comUndoLivestlyThis List Ranks The Dog Breeds You’ll Want To Avoid At All CostsLivestlyUndoHomeAdvisor ProsHave You Tried HomeAdvisor to Find Renovation Jobs?HomeAdvisor ProsUndolast_img read more

Bombay HC upholds death penalty clause for repeat offenders in rape casesBombay

first_img COMMENT SHARE SHARE EMAIL Under an amendment to section 376 (e) of the IPC, repeat offenders in rape cases faced life imprisonment or a death penalty. Representative image   –  Shutterstock Published on June 03, 2019center_img Under an amendment to section 376 (e) of the IPC, repeat offenders in rape cases faced life imprisonment or a death penalty The Bombay High Court on Monday upheld the Constitutional validity of an amended section of the Indian Penal Code (IPC) under which repeat offenders in rape cases can be awarded life imprisonment or death penalty.A division bench of Justices B P Dharmadhikari and Revati Mohite Dere dismissed petitions filed by three convicts in the Shakti Mill gangrape case challenging Constitutional validity of the legal provisions under which they were sentenced to death in 2014.Under an amendment to section 376 (e) of the IPC, repeat offenders in rape cases faced life imprisonment or a death penalty.The amendment was made after the gangrape of a 23- year-old woman in Delhi in 2012. SHARE COMMENTSlast_img read more