The AFC Bournemouth footballer has signed a three-and-a-half year contract after he impressed everybody when playing for the team’s senior squad.19-year-old Kyle Taylor is a product of AFC Bournemouth Academy.The youngster was spotted by academy manager Joe Roach.And now the midfielder has been called to the first team and has signed a new three-and-a-half year contract with the English Premier League club.“Kyle has been with us for the whole length of the journey and it’s great to see,” Roach told the team’s official website.“He was fairly slight when he was younger but he has always been very technical and a nice player who caught the eye.”Brad Smith is loving his time at MLS Manuel R. Medina – August 27, 2019 Smith has been loaned from AFC Bournemouth to Seattle Sounders for a whole season, and the Australian footballer is enjoying his time there.“He was given an early scholarship, which is not the norm, and played up a year and did well,” he explained.“Like with all young players, there were areas of his game he needed to improve.”“When Carl Fletcher and I came back to the club in 2014, Kyle was at the start of his scholarship journey,” he added.“We viewed him in terms of how we were going to fit him in with regard to his physical side and perhaps trying to be a little stronger mentally.”“We spoke to Kyle and his parents and outlined what we felt he needed to do to make sure he got over the line at the end of the scholarship. It was quite strong but it centered on what he needed to focus on,” Roach continued.“His response was fantastic. It was one of those moments I remember, as I have with others when one little seed made sure he focused on where he should be.”
October 28, 2018 SWAT team called after reports of gunfire in Bonita, suspect arrested KUSI Newsroom KUSI Newsroom, BONITA (KUSI) — Reports of gunfire in a neighborhood in Bonita brought out a SWAT team, where an alleged gunman was arrested and nine other people were detained Sunday.No one was hurt, and sheriff’s deputies ultimately arrested one person in connection with the incident.A caller told police just before 4 a.m. Sunday that they could hear gunshots in a neighborhood east of Briarwood Road and south of state Route 54, San Diego County Sheriff’s Department Lt. Michael McNeill said.A Sheriff’s Department SWAT team headed to the 5400 block of Robinwood Road, where they found shell casings and live rounds in the driveway of a house and initially detained nine people for questioning. Officers from the San Diego and Chula Vista police departments also responded to help.While deputies and officers were conducting their investigation, they heard several more gunshots coming from nearby, McNeill said.Deputies and officers saw a man run away, and they briefly chased him but lost sight of him, according to a Sheriff’s Department news release. With the help of a police dog, they were able to find the man hiding in shrubs outside an apartment complex, and they detained him as well.Deputies also found a gun and a magazine in the area, McNeill said.The man, Salvador Barajas, 25, was first taken to a hospital for a medical evaluation before being booked into jail on suspicion of negligent discharge of a firearm. Posted: October 28, 2018 Categories: Local San Diego News FacebookTwitter
111 tags have been attached to halibut through Kachemak Bay, tags are worth $250, $500, $1000 with two tags big tags: Homer Charter Association tag worth $10,000 and the Homer Chamber of Commerce tag worth $25,000. The Homer Jackpot Halibut Derby is the longest running halibut derby in the state of Alaska, with over $90,000.00 in CASH prizes, and runs May 15 to September 15 each year. You can purchase Derby tickets at businesses all over Homer, and tickets are required in order to participate. Winners will be announced at the September 20th Jackpot Halibut Derby Gala. Facebook0TwitterEmailPrintFriendly分享The Homer Chamber of Commerce & Visitor Center’s 33rd Annual Jackpot Halibut Derby starts tomorrow, May 15. Derby info available at: www.HomerAlaska.org/jackpot-halibut-derby.html
News Twitter The creepy “bury a friend” video, directed by horror film director Michael Chaves, features plenty of scary movie-worthy moments including a dark apartment, gloved hands forcefully grabbing Eilish and a possessed version of the young star sauntering through the shadows.The song will be featured on the upcoming album, whose track list reveals the album will give us 11 new songs, along with three previously-released ones. In addition to “bury a friend,” two tracks released in 2018 will be on the album, “you should see me in a crown” and “when the party’s over.”Earlier in January, Eilish released “WHEN I WAS OLDER,” a song inspired by ROMA, the Netflix film directed by Alfonso Cuarón. She will be touring Europe in February and March, followed by a stop in Indio, Calif. for both weekends of Coachella 2019.WHEN WE ALL FALL ASLEEP, WHERE DO WE GO? is available for pre-order now on Eilish’s website, where you can also find her tour dates.Billie Eilish: “People Underestimate The Power Of A Young Mind”Read more Facebook Billie Eilish Shares New Song, Album Release Date billie-eilish-drops-new-song-reveals-debut-album-release-date Email Billie Eilish Drops New Song, Reveals Debut Album Release Date The 17-year-old anti-popstar just released “bury a friend” off of her newly announced upcoming debut LP, ‘WHEN WE ALL FALL ASLEEP, WHERE DO WE GO?’Ana YglesiasGRAMMYs Jan 30, 2019 – 12:11 pm Today 17-year-old genre-nonconforming Billie Eilish shared the release date for her highly anticipated debut album, along with a new song from it. The dark single “bury a friend” and its spooky music video dropped today and WHEN WE ALL FALL ASLEEP, WHERE DO WE GO? will be released on March 29.
Game of Thrones season 8, episode 4: How to watch, leaks, recaps, avoiding spoilers and how to stream HBO without cable Thanos vs. Game of Thrones Night King: Here’s who’d win Game of Thrones season 8: How to adjust your TV for a cinematic picture Here’s me thinking this episode would be a celebration #GameOfThrones pic.twitter.com/1BQiCa6aQw— Joeyyy (@_Joseph590) May 6, 2019 The 38 most gut-wrenching Game of Thrones deaths, ranked Comments OH NOOOOOO. NOT THE DRAGONNNNNNN. #GoT #ThronesYall pic.twitter.com/52CoNbI6oc— Brittany Packnett (@MsPackyetti) May 6, 2019 Game of Thrones images too dark? We can help *MILD SPOILERS*… Culture TV and Movies Now playing: Watch this: WHAT THE WHOLE FUCK IS HAPPENING?!?!?! THIS FUCKIN ASSHOLE!!!!!!!!!! BURN THEM ALL!!! @HBO @GameOfThrones #GoT #Season8 #DemThrones #Episode4— T-Pain (@TPAIN) May 6, 2019 Did we just lose another dragon?!? Wtf?!? #GameofThrones pic.twitter.com/HTngwEfAJ6— the.blogging.jedi (@TonyStarksWard) May 6, 2019 Rhaegal after being shot by Euron three times #GOT #GameofThrones pic.twitter.com/PcghYP18oV— colby (@originalgenome) May 6, 2019 Related stories Not the dragon!! Not him!! He should stay back! #GameofThrones pic.twitter.com/fguDMwcx6K— Yerlin (@Marlet_Yerlin) May 6, 2019 NOOOOOO THAT DID NOT JUST HAPPEN #GameOfThrones pic.twitter.com/Li74D2gUiL— t h o m a s (@RIPeterParker_) May 6, 2019 Tags Me: “Oh, he only got hit by one spear he might be okay…”*Gets shot in the throat***Sinks to the bottom of the ocean**#GameofThrones #Rhaegal pic.twitter.com/uN1tbkEqyk— Dr.Pibb🌶️ (@MichaelDiAcri) May 6, 2019 Why? HBO Look, we’re used to heart-wrenching deaths on Game of Thrones, but this is different. This totally sucks.What are you doing to us here? Why would you do this?OK, here’s your obligatory spoiler warning for episode 4 of this final season. Can we talk now? OK, let’s talk.They killed a dragon. They killed another goddamn dragon. Rhaegal to be specific. People are upset. Hell, I’m upset. The Night King doing the whole “you’re an ice dragon now” to Viserion was pretty bad, but this might actually be worse.Mainly because of who did the killing. 38 Photos I can’t handle Dany losing anymore dragons #GOT #GameofThrones pic.twitter.com/zce6jJxIFK— colby (@originalgenome) May 6, 2019 5:13 Rhaegal didn’t deserve surviving his ice dragon brother to be killed by bitch ass Euron!!!! #GoT pic.twitter.com/F2XjqDPLeB— MissFit Harley (@MissfitHarley) May 6, 2019 And then there was 1! 😢😩 #GameOfThrones #GOT— MeLAnIn JunKIE (@xLuv_N_Myself) May 6, 2019 Share your voice 8 RIP Rhaegal, you were almost all healed up for battle, you sweet baby you. RIP Missandei, you were the realest and you had the most poppinest wash-n-go in all the 7 Kingdoms until the very end. pic.twitter.com/MYA6KisIWh— 🐝HTHMSCTHMING🐝 (@_BeNiceOrLeave) May 6, 2019 RIP Rhaegal, you were almost all healed up for battle, you sweet baby you. RIP Missandei, you were the realest and you had the most poppinest wash-n-go in all the 7 Kingdoms until the very end. pic.twitter.com/MYA6KisIWh— 🐝HTHMSCTHMING🐝 (@_BeNiceOrLeave) May 6, 2019 Rhaegal died thanks to Euron Greyjoy and Cersei’s gigantic dragon crossbow thing — this is a problem. Euron sucks. Not in a good, “Hi, I’m Joffrey the best villain in TV history kind of way.” In a bad, “my character is a bit weird and people don’t really like me” kind of way. In wrestling, they call this “X-Pac heat.”Anyway, Twitter got real upset about Rhaegon essentially getting murked by Euron’s fleet. Rightfully so in my humble opinion. With Rhaegal kicking the bucket and Jon Snow putting Ghost up for adoption, it was truly a difficult episode for the pets. Game of Thrones
Enlarge ImageTuro hasn’t finalized the design aspect just yet, but here’s an idea of what to expect. Turo Nearly every automaker has a connected-car element that allows owners to manipulate the car from afar. Smartcar created software that works across these borders, and its latest partnership could make renting some other person’s car a little easier.Turo, a peer-to-peer car sharing startup, announced on Monday that it has partnered with Smartcar to put its system to use as part of the rental process. Normally, when renting somebody else’s car on Turo, that person usually needs to be around to hand over the key. Instead of that, Smartcar’s system uses renters’ phones to wirelessly locate, lock and unlock cars without the need for the “hosts,” as Turo calls them, to be present.Here’s how it works. Hosts who have eligible vehicles will be notified, and using Smartcar’s backend software, they can connect their vehicle account with their Turo account. Once that happens, renters can use their own phone to find and unlock the vehicle. Most OEMs’ connected-car systems don’t let phones work as keys, though, and that’s the case here — the keys can be found inside the vehicle after unlocking, and that’s where to leave ’em when the rental term ends.It’s a huge boon for busy hosts. Now, they won’t need to move their schedules around to accommodate renters, allowing them to maintain an additional revenue stream with less potential annoyance. Some similar systems require hardware in the car, but not this one — it’s all done over the air, no OBD-II dongles or anything of that sort.As with many other fledgling partnerships, this one will start small. Turo will offer its Smartcar system in California and New Jersey to start, with the intention of rolling it out to the entire country later in 2019. Originally published May 6, 12:09 p.m. PT. Update, 12:46 p.m.: Added information regarding how the traditional car key factors into this scheme. 2019 Ford Shelby GT-S Mustang supercharges the rental car experience Share your voice 2020 Hyundai Palisade review: Posh enough to make Genesis jealous More From Roadshow 88 Photos 0 Tags 2020 Kia Telluride review: Kia’s new SUV has big style and bigger value Auto Tech Car Games and Apps Post a comment 2020 BMW M340i review: A dash of M makes everything better
Doctor visits are climbing and pediatric deaths from the illness are up as well. What makes it so severe? Dr. Amber Robins of Georgetown University joins John Yang to discuss the flu vaccine and other tips for prevention. Share
×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 América Móvil general director Daniel Hajj has announced that Carlos Slim’s Mexican conglomerate plans to invest $8.5 billion in Latin American in 2019, focusing primarily on fiber-optic infrastructure and updated mobile technologies such as 4.5G and 5gG.In a conference call with analysts, following the company’s recap of fourth quarter results, Hajj laid out the company’s intentions, while also stating that the company is planning to provide triple-play services in Mexico.During the fourth quarter of 2018, América Móvil recorded a net profit of $492.4 million, reversing losses of $546.4 million over that same period in 2017, according to the company’s financial and operating report.In that time almost 200,000 subscribers were added in Mexico. In total, its subscriber base increased by 7.2% from the previous year. Popular on Variety Last December, Gabriel Contreras, president of the Mexico’s Federal Telecommunications Institute (IFT), indicated that a subsidiary of América Móvil had applied for a license to provide pay TV services. Given its dominate position in the telco sector, America Movil itself is forbidden from providing pay TV directly.According to Hajj, the company’s experience in other Latin American countries is cause for confidence. Once permission to broadcast pay TV is granted, “We can do it [offer triple play] quickly… We have experience in other countries in addition to commercial agreements for content.”Last month América Móvil announced it had acquired 100% of Guatemala’s Telefónica subsidiary, and reached an agreement to buy 99.3% of El Salvador’s subsidiary as well.
Kalna (WB): An alleged serial killer, who targeted middle-aged women when they were alone at home, has been arrested in this small town in East Burdwan district, the police said Tuesday. Kamaruzzaman Sarkar, a small-time trader of discarded materials, is a suspect in the killing of five women and injuring several others in East Burdwan and neighbouring Hooghly districts, the police said. The 42-year old Sarkar, attired in trendy clothes, would enter homes during afternoon hours in the pretext of taking electricity meter readings and then pounce upon the women with a cycle chain and an iron rod, Also Read – Rs 13,000 crore investment to provide 2 lakh jobs: Mamata East Burdwan Superintendent of Police, Bhaskar Mukhopadhyay said that the district court has on Monday remanded Sarkar to 12 days in police custody in connection with the murder of Putul Majhi at Goara village here on May 21. The SP said that the police sought Sarkar’s custody to interrogate him on his role in the other four murders, all of which were committed in the same manner. Some women had managed to escape attacks by the diminutive man, whose modus operandi was to strangulate them with a chain and then hit them on the head to ensure death. Also Read – Lightning kills 8, injures 16 in state “Though he would escape with some valuables from the houses of his victims, but theft does not seem to be the motive. Murdering the women seemed to be his main target,” Mukhopadhyay said. Police said that the accused had allegedly inserted sharp materials into the private parts of some of his victims following their death. “We are interrogating him to understand why he targeted middle-aged women,” the SP said. Sarkar, married with three children, may have had some grudge on women of the said age bracket over some personal issue and this angle is being investigated, said a police officer. The accused, riding a red motorbike and wearing a red helmet was arrested in Kalna on Sunday after being stopped by a civic police volunteer on suspicion. Following the murder of Putul Majhi, the district police had distributed CCTV footage of a suspect wearing a red helmet and riding a red motorbike to all police stations. Sarkar is suspected to have killed Pushpa Das of Anukhal area on January 27, the police said. On April 4, Rita Roy and Mamata Kishku were killed within a few hours of each other in Memari police station area of the district. One Soni Yadav of Memari was also killed in the same manner, the police said. Swarupa Bibi of Rongpara here was one of the lucky few to have escaped his attack. She was allegedly attacked from behind with a cycle chain, but she managed to shrug off the attacker and raise an alarm.
France Télévisions yesterday officially launched its new video-on-demand service Pluzz VàD, complementing its existing Plus seven-day catch-up TV service.Pluzz VàD, which will be available via IPTV, the internet, tablets and smartphones, is launching with a catalogue of about 3,000 titles, including drama series, documentaries, magazine and kids programming, live events and French and international movies, with about 500 titles available in HD. France Télévisions has promise that 200 new titles will be added each month.The broadcaster said it had struck deals with the main French producers and with French film studios including Gaumont, Pathé, Europa, StudioCanal, TF1 and BacFilms. Discussions with Hollywood studios and still in progress. TV shows will be available for between €1.50 and €3, while movies are likely to be in priced around €4.99.The service will initially be offered by service provider Free in its IPTV offering. Hubee is supplying the technology platform for Pluzz VàD and the service uses Adobe’s Flash technology and DRM.
ANGA COM in Cologne and the DTG UK UHD Forum in London each held corresponding demos of live decoding of 4K content compressed with HEVC yesterday.In London visitors to the DTG conference were able to see live decoding and display of 10-bit 50Hz 2160p content compressed with HEVC in what was touted as the first example of decoding using silicon in real time.At ANGA, the corresponding demo used the latest Broadcom BCM7445 chipset with support for 60Hz progressive display.“Broadcom’s early entry in Ultra HD, beginning with the BCM7445 UltraHD video decoder at CES 2013, has allowed us to deliver multiple advanced SoCs with market specific features and price points today,” said Rich Nelson, senior vice president of marketing, broadband communications group, Broadcom Corporation.“Our continued commitment to developing industry protocols and working closely with our partners is helping to bring the clarity and brilliance of Ultra HD TV to the home, while delivering economics that work for service providers.”
Hud WoodleChannel operator Scripps Networks International has created a new distribution division, which will make its market debut at MIPCOM with a 1,200 hour slate.Scripp’s veteran Hud Woodle will run the new unit as vice president, international program licensing and distribution. Based in New York, he will report to company CFO Simone Nardi.“As Scripps Networks’ international business continues to expand, bringing our international program sales and distribution function in-house enables us to more closely coordinate our international and regional channel and programming priorities,” said Nardi.He added: “As the global media leader in home, food and travel, Scripps Networks offers premium aspirational content that resonates with a global audience.”Woodle will manage all aspects of the company’s program sales and content distribution activities, working with regional managing directors in London, Singapore and São Paulo. The moniker for the new unit will be Scripps Networks International Program Sales and Distribution.Woodle will also oversee program delivery operations for the company’s international channels. Scripps said it is currently in the process of building his program sales team with members based in New York, London, Singapore and Sydney being recruited.Passion Distribution has been selling Scripps content and will continue to partner with Scripps Networks over the next six months as that deal is phased out. While it remains in place, Passion will launch a new slate of new original content from Scripps as part of its MIPCOM slate.Woodle joined Scripps Networks International eight years ago as Director of Program Sales where he was responsible for program sales in Asia and Latin America. In 2009, Woodle successfully launched Food Network in Asia and secured channel distribution across key platforms in Southeast Asia. He went on to become the general manager of Food Network in Asia, overseeing network operations and successfully negotiating affiliate agreements in the region.
Digital UK has published the technical specification for connected TV service Freeview Play, opening it up to broadcasters, platforms and equipment manufacturers.The specification, which detail the technologies required to design and implement Freeview Play TVs and boxes, was previously only available via formal registration.Digital UK, a non-profit organisation that supports the UK’s terrestrial TV service and led the led technical development of Freeview Play, said that the move to open up the document follows “strong interest” in Freeview play from UK manufacturers and international markets since its launch in October 2015.“Our decision to openly publish the technical specifications for Freeview Play will make it easier for manufacturers to bring products to market and help broadcasters around the world develop their own enhanced, hybrid TV services,” said James Jackson, technical director at Digital UK.Freeview Play is currently available in a range of Panasonic TVs and Panasonic and Humax recorders. LG, Manhattan and multi-brand manufacturer Vestel are also expected to release Freeview Play- products this year.All Freeview Play products meet existing standards for Freeview HD and include features such as HTML 5-based support for advanced player applications, a seven-day scroll-back TV guide, enhanced EPG data, interactive services like BBC Red Button+, adaptive bitrate streaming and on-demand ad insertion.
Jim Rickards’ Secret Accounting Career In 1977, before most of today’s Wall Street analysts were even born, Jim Rickards was doing complex tax and accounting work at Citibank. Now he has uncovered the biggest accounting hoax since Enron… one that could wipe out millions of Americans. Will you be a victim of this accounting scandal? Click here to find out. Recommended Links One of the world’s most important markets continues to flash danger signs… Regular readers know we keep close tabs on the bond market. The bond market is where individuals, companies, and governments go to borrow money. The U.S. bond market is about twice as large as the U.S. stock market. That’s one reason the bond market can signal trouble before the stock market. • The junk bond market is where companies with shaky finances borrow money… Junk bonds are riskier than bonds issued by healthy companies, so they pay higher yields. When the economy slows, companies in bad financial shape often feel it first. That’s why economic trouble tends to show up in the junk bond market early on. • Junks bonds are set to have their first down year since the financial crisis… On Monday, The Wall Street Journal reported that U.S. junk bonds are down 2% on the year. If they end the year down, it would be their first losing year since 2008. • Bond defaults are at their highest level since 2009… Worldwide, companies have already defaulted on $95 billion in debt this year. That translates to 102 corporate defaults, or 42 more than last year. U.S. companies account for over half of these defaults. • Moreover, the U.S. energy sector accounts for 26% of global defaults this year… Casey readers know the U.S. energy market is struggling… Yesterday, the price of oil hit a new six-year low. It’s plunged 66% since last June. And the price of natural gas has plunged 56% since last summer. Most oil and gas companies’ profits have plummeted. As a result, companies that borrowed big before energy prices crashed are struggling to pay back their loans. • Credit rating agency Standard & Poor’s says half of all energy junk bonds are distressed… A distressed bond has a high risk of default. And the trouble isn’t isolated to energy bonds. Last week, Bloomberg Business reported that 20% of all U.S. junk bonds are now distressed. That’s the highest level since September 2009. • Corporate defaults could double in 2016… So far, only 2.6% of junk bonds have defaulted this year. However, that figure will likely jump soon. On Monday, The Wall Street Journal reported that defaults are expected to nearly double to 4.6% next year. If that happens, junk bonds would pass their 30-year average default rate of 3.8%. That also hasn’t happened since 2009. • Meanwhile, the U.S. stock market is showing big cracks… Last week, we explained how a handful of huge companies are making the U.S. stock market look healthier than it really is. This includes Google (GOOG), Microsoft (MSFT), Amazon (AMZN), Facebook (FB), and Netflix (NFLX). When most investors talk about “the stock market,” they’re talking about the popular S&P 500 index. The S&P 500 is weighted by company size, which means bigger companies affect its performance far more than smaller companies. For example, Google is the second-largest company in the S&P 500. It’s up 43% on the year. Amazon is the sixth-largest company. It’s up 113%. Facebook is the eighth-largest. It’s up 35%. Meanwhile, S&P 500 stocks are trading 18% below their 52-week highs, on average. • This chart shows what’s really happening in the stock market… It’s one of the most important charts in the world right now… It compares the S&P 500 with a version of the S&P that gives equal weight to every company. In the equally weighted S&P, toymaker Hasbro (HAS) has as much weight as Google, which is 61 times bigger than Hasbro. Only way for Americans to legally pay close to ZERO taxes 70-year-old multimillionaire has revealed greatest – and least known – American tax “loophole.” Click here to get the full details. – • The U.S. stock market flashed the same red flag in 1999… A handful of big stocks pulled the major indices higher that year, while most U.S. stocks struggled. By 2000, the S&P 500 turned down and went on to lose 48% in 32 months. The NASDAQ crashed 78% in the same time. The U.S. stock market is like a healthy-looking tree that’s actually rotting on the inside. Eventually, when the largest stocks can’t prop it up anymore, the entire tree is going to fall. • We recommend investing with extreme caution right now… You should hold a significant amount of cash and some physical gold. You may also want to hedge your portfolio by shorting (betting against) stocks likely to crash hard during the next big downturn. This could mean shorting very expensive stocks. It could also mean shorting businesses that will struggle to make money during a prolonged economic slowdown. We recently recorded a video presentation on the topic of investing during difficult times. Doug Casey, founder of Casey Research, gave his advice on how to protect your money and make more money during a major market collapse. Click here to watch – it’s free. Chart of the Day Here’s another clue U.S. stocks are topping out… Professional investors often look at “spreads” to gauge the market’s strength. A spread is the difference between two prices or interest rates. One important spread subtracts the interest rate paid by junk bonds from the interest rate paid by U.S. Treasuries. U.S. Treasuries are bonds issued by the U.S. government, which is widely considered one of the safest borrowers in the world. Junk bonds, on the other hand, are issued by riskier borrowers. Today, the interest rate on Treasuries is 2.1% and the average interest rate on junk bonds is 8.8%. So the “spread” is 6.7%. When the economy is humming along, this spread typically gets smaller. Companies generally make good on their bonds during good economic times, so investors don’t demand a big interest rate premium. However, when the spread starts to get bigger, it’s a sign of trouble ahead for the stock market. For example, this spread started to get bigger in the summer of 2007. Smart investors knew this was a bad sign. They got out of the stock market and saved a ton of money. As you likely remember, the S&P 500 peaked in October 2007, and went on to crash 57%. For the first time in four years, this spread is getting significantly bigger. As you can see, the U.S. stock market and spread moved together while stocks were in a clear-cut bull market through mid-2014 (the spread is inverted on the chart below). Then, they diverged. The spread has more than doubled, while the S&P 500 remains near all-time highs. This is another reason to be very cautious in the stock market today. These two indices tracked each other for most of 2015. However, in recent weeks the S&P 500 has pulled ahead of the equally weighted S&P, which is now down 4% on the year. This is a big red flag. It’s confirmation that a few big companies are holding up the stock market. — Regards, Justin Spittler Delray Beach, Florida December 11, 2015 We want to hear from you. If you have a question or comment, please send it to email@example.com. We read every email that comes in, and we’ll publish comments, questions, and answers that we think other readers will find useful.
Just over four years ago, on July 17, 2014, six delegates on their way to the International AIDS Conference died in the shoot-down of Malaysia Airlines Flight 17 over eastern Ukraine.The delegates were among the 298 people killed hours after their flight took off from Amsterdam.International investigations concluded that the missile that downed the jet originated with the Russian military, which has denied involvement. This year, Amsterdam is where thousands of experts in public health and global development are gathering for the International AIDS Conference, which begins on Monday.”I’m hopeful that people will still remember them,” Owen Ryan, the outgoing executive director of the International AIDS Society, says of the colleagues he lost in the AIDS prevention research and activism community that day. Ryan told NPR’s Korva Coleman he wants their legacy to help draw attention to AIDS as a continuing crisis, “and know it’s important we keep this fight going.”About 37 million people around the world were living with HIV/AIDS in 2017, according to the World Health Organization. The group says 940,000 people died of HIV-related diseases last year. On the eve of the 22nd International AIDS Conference, Ryan talked with NPR about the current state of the AIDS crisis around the world and why it’s important to keep funding AIDS prevention efforts.Interview HighlightsOn Joep Lange, a former president of the International AIDS Society who died on MH17It’s hard to describe in short ways all the ways that Joep had kind of really transformed the HIV movement. One very large way though was how he made the world wake up to the need for antiretroviral treatment in Africa. He was one of the first researchers, scientists, activists who was forcing donor governments to face the problems that were in Africa — and to get rid of the impediments that were keeping people away from lifesaving treatment.He is in large part to thank for many of the millions of people who are on treatment today. On what can slow down the rate of current AIDS infectionsHonestly, what needs to be done is this sense of complacency that has settled on many of us. There’s really this feeling in many parts of the world that AIDS is over, and that is really far from true.It’s one of the reasons we miss Joep the most right now — he had an unbelievable ability to speak truth to power, regardless of who he’s speaking to. He just knew how to go right to them and say, “What you believe is not true and we need more money for this.”On the development of drugs to stop AIDSFor one of the first times, we’re doing a large-scale clinical trial for vaccines in South Africa. And South Africa’s one of those countries where if we can get it right there, we can get it right in a lot of places around the world. But until we get more people on treatment in the short term, we’re going to keep trying to play catch-up. So we’re really hoping we can do both things at the same time: get people on treatment, and then longer-term prevention options.On particular regions where the AIDS crisis is growingEastern Europe and Central Asia is a big focus of this conference. You’ve seen that over time as economies have improved, donors have walked away. And with them walking away has walked away political will. So in many places, and this also includes Russia, you’ve seen the epidemic come back with force. And you’re seeing in urban centers and rural areas people who are just completely away from treatment and this massive explosion in new infections and I think people just don’t realize it.On preventing future epidemicsWe always have to be aware and it’s the exact moment you take your finger off the pulse of epidemiology that you start to see problems occur. We need to fund the systems that keep us vigilant against the next great disease that’s coming — ’cause we know it’ll happen. We’ve seen this with Ebola, we’ve seen this with SARS in the past. We need to keep things like the CDC and WHO — we need to keep them vibrant and strong and paying attention to all of this. Copyright 2018 NPR. To see more, visit http://www.npr.org/.
Reviewed by James Ives, M.Psych. (Editor)May 6 2019According to a new research, circulating tumor DNA can be used detect treatment options for ovarian cancer patients who don’t benefit from chemotherapy.High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer. The HGSOC tumors consist of several heterogeneous cell populations with a large number of mutations. This genetic variability makes it difficult to find drugs that would kill all the cancer cells, and to which the cells would not become resistant during treatment.Over half of the patients diagnosed with high-grade serous ovarian cancer die within five years of diagnosis, that is, annually more than 150000 women globally. To improve the efficacy of HGSOC treatment, a research group from University of Helsinki, together with researchers from University of Turku and Turku University Hospital, have now studied the use of circulating tumor DNA in finding precision medicine-based treatments for the disease.Circulating tumor DNA refers to tumor-derived cell-free DNA in the bloodstream. Circulating tumor DNA detection is a minimally invasive technique that offers dynamic “molecular snapshots” of genomic alterations in cancer.”Analyzing circulating tumor DNA enables us to detect genomic alterations also in late stage cancers in which taking biopsies from the tumor is difficult or even impossible. In the current research, we demonstrated that circulating tumor DNA can be used to monitor the patient responses to treatment, and find drug combinations to target the Achilles’ heels of the tumor’s genomic profile,” says Professor Sampsa Hautaniemi, director of the Systems Oncology Research Program in the Faculty of Medicine at University of Helsinki.Related StoriesSpecial blood test may predict relapse risk for breast cancer patientsBacteria in the birth canal linked to lower risk of ovarian cancerUsing machine learning algorithm to accurately diagnose breast cancerThe results were published in JCO Precision Oncology.Hautaniemi’s research group has implemented a clinical circulating tumor DNA workflow to detect clinically actionable alterations in more than 500 cancer-related genes.In the present study, the researchers analyzed 78 circulating tumor DNA samples from 12 ovarian cancer patients before, during and after the treatment using bioinformatics analysis, and in-house Translational Oncology Knowledgebase to detect clinically actionable genomic alterations.DNA alterations associated with clinically available drugs were detected in 58% of the patients. The treatment of one patient has already been tailored successfully based on the results. For the other patients the results may be useful if their cancer relapses.The results demonstrate a proof-of-concept for using circulating tumor DNA to guide clinical decisions. Furthermore, the results show that longitudinal circulating tumor DNA samples can be used to identify poor-responding patients after first cycles of chemotherapy.In addition, the researchers provide the first comprehensive, open-source circulating tumor DNA workflow for detecting clinically actionable alterations in solid cancers.”The prognosis of ovarian cancer patients is still poor. However, the future looks brighter as research has discovered targeted therapies for the genomic alterations also in ovarian cancer tumors. We are currently in the forefront of the precision medicine for ovarian cancer. Our goal is to find out how ovarian cancer becomes resistant to current treatments, and use this knowledge in finding more effective precision treatments,” Hautaniemi says. Sources:The University of Helsinki.Journal reference:Jaana Oikkonen et al. (2019) Prospective longitudinal ctDNA workflow reveals clinically actionable alterations in ovarian cancer. JCO Precision Oncology. doi.org/10.1200/PO.18.00343.
Ivanka Trump, daughter of US President Donald Trump, hosted a White House meeting on sex trafficking on March 13; she is seated between Senators Rob Portman and Amy Klobuchar Explore further The move by Craigslist suggested that websites may shutter or censor some content to avoid prosecution under the Stop Enabling Sex Traffickers Act (SESTA) approved by Congress this week and awaiting President Donald Trump’s signature. Craigslist said in a statement it ended personals over concerns the law could subject websites to criminal and civil liability for third-party content.”Any tool or service can be misused,” the statement said.”We can’t take such risk without jeopardizing all our other services, so we are regretfully taking craigslist personals offline. Hopefully we can bring them back some day.”Lawmakers contended websites such as Backpage facilitated sexual exploitation including prostitution and human trafficking through their adult services listings. Craigslist ended adult services ads in 2010.Critics of the legislation argued that it undermine a basic underpinning of the internet, which enables websites to host information from third parties without liability.The measure “creates a host of obstacles to the free and open internet,” said Emma Llanso of the Center for Democracy and Technology, a digital rights organizations.Robyn Greene of the New America Foundation’s Open Technology Institute said the law “will result in increased censorship and harm the internet economy, hitting small businesses and start-ups the hardest, but it won’t effectively combat human trafficking.”Greene added that the measure “could even do real harm by driving the perpetrators of these horrible crimes further underground.”The White House has endorsed the bill, and Trump’s daughter Ivanka hosted a meeting earlier this month with sponsors of the legislation, saying it was needed to help crack down on human trafficking using the internet. Citation: Craigslist ends personal ads after US sex trafficking bill passes (2018, March 23) retrieved 18 July 2019 from https://phys.org/news/2018-03-craigslist-personal-ads-sex-trafficking.html Craigslist said Friday it shut down its personal ads section as concerns grew over unintended consequences of a law approved by Congress which could hold websites liable for promoting sex trafficking. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2018 AFP Tech sector battles US lawmakers on sex trafficking bill
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. MSU has developed sensors that can detect road wear, bridge defects and more. Some sensors have already been deployed to Michigan’s iconic Mackinac Bridge. Credit: MSU “The successful large-scale deployment of this novel low-cost sensing technology will dramatically transform the economics of bridge preservation/management and ultimately improve the serviceability of bridges,” said Nizar Lajnef, MSU associate professor of civil and environmental engineering. “We also will explore how the collected data could be used for improved cost-effective, condition-based maintenance of the Mackinac Bridge structural components. We are excited that this will be the first fully instrumented bridge in the country using advanced wireless and self-powered monitoring technology.”Beginning in 2016, Lajnef and Shantanu Chakrabartty, WUSTL professor, started deploying prototype sensors beneath the bridge as part of a demonstration project sponsored by the Federal Highway Administration. The Mackinac Bridge provided a high-profile testing ground for these self-powered sensors. Since then, the new and improved versions of the self-powered sensors have been developed as a part of the National Science Foundation’s Cyber-physical Systems program and have been successfully deployed on the bridge.Several of the sensors’ features make them attractive to infrastructure managers. Because the sensors have no external power source, they eliminate the issue of requiring battery changes or wiring to power sources. They also don’t need wires to access the data they collect; staff can access the information wirelessly.”In addition to being a statewide need, the development of effective methods for preserving our transportation infrastructure systems is a critical national need,” Lajnef said. “Through this large-scale deployment, we would show that the system can autonomously monitor the loading experienced by the bridge components, and that the information from the sensors can be collected without significant human intervention and at significantly low cost.”MSU is an ideal partner in advances such as these due to the university’s commitment to test emerging technologies for new mobility solutions. As part of this initiative, the university is well equipped to advance mobility by leveraging its expertise and collaborating with strong industry partners.MBA staff will assist with installation of the additional sensors, offering equipment and access to the bridge. MBA will retain ownership of the data gathered by the sensors, with WUSTL providing the sensor prototypes and MSU providing tools to analyze and interpret that data for bridge staff to use in guiding engineering and maintenance decisions. The team can use the data for research publication with approval from MBA.The team plans to start installation of the additional and improved sensors this summer. The researchers will coordinate installation timing and any necessary lane closures with MBA staff. Citation: Scaling up innovative sensor installation on the Mighty Mac (2019, March 5) retrieved 17 July 2019 from https://phys.org/news/2019-03-scaling-sensor-mighty-mac.html Explore further Building smart infrastructure sensors The first 20 prototype infrastructure sensors installed in 2016 on the Mackinac Bridge, powered solely by vibrations from traffic, have proven their durability and performed as intended. Now researchers from Michigan State University and Washington University in St. Louis are ready to roll out the next phase of testing, installing up to 2,000 of the tiny devices to explore the logistics of a large-scale deployment and provide useful monitoring data to the Mackinac Bridge Authority. Provided by Michigan State University